Television Plug-In Drug Assignment Example | Topics and Well Written Essays - 500 words

Television Plug-In Drug - Assignment Example Ms. Winn emphasized the points in her essay through emotional appeal on some of the aspects such as deteriorating family relationships since even during meal times the television is switched on. Ms. Winn stated that parents have settled for the convenient lifestyle provided by the television, it gives the children company throughout and therefore also acts as a babysitter. What I found lacking in Ms. Winn’s work was significant empirical evidence that would substantiate her work. Mostly she has used an emotional appeal to sway the readers off the importance of evidence that would justify her stance. Therefore, in order to get a clearer picture of the issue I looked for some empirical evidence on the topic which I researched the topic â€Å"Research on Television Addiction† on EBSCO host and found in the article â€Å"Measuring Television Addiction† by Cary W. Horvath. The article was published in the Journal of Broadcasting & Electronic Media, which I believe is a very authentic source of information, moreover the author Ms. Horvath is Assistant Professor in the Department of Communication and Theater at Youngstown State University, which for me adds a lot more value to the credibility of the research. Ms.

Wall street Journal write-ups Essay Example | Topics and Well Written Essays - 500 words

Wall street Journal write-ups - Essay Example Mention also of subprime lending as a possible instigator. Outlining further the history of economic crisis and how such circumstances play into crisis like these. How these crisis can have multiple causes and many intricacies. In the process of moving forward to find a solution to this financial crisis, many different options are available for consideration. The need to look at a situation like an economic crisis with logic and rational thinking, rather than emotions. Social Psychologist suggestion that when in doubt, people look to believe whatever they can to get them through. The article makes reference to the issue of regulatory practices which goes with the discussion in Chapter 12 having to do with regulation and its impact. Detailed in the section â€Å"Effect of Regulation on the Actions of Employers† Pages 573-575. The discussion which Claomiris sets forth to have is quite relevant for the times. The issue of how the many different circumstances that can occur could lead to such an economic downturn for many people. It is of the utmost importance to look at the larger picture that comes with the issue of economics and how best to aid an ailing economy. To formulate such solutions without the presence of emotional bias, but rather an educated approach with a rational mind. As is the case with many things, the history of what has happened in the economy before, both at home and abroad, is something that can be quite useful to analyze and consider as Claomiris suggests in his writing. Countless economic crisis have in fact occurred over the years. Each situation being individually different, but also having a central theme that can be tied in with others to find a central path towards a solution. As there are multiple circumstances at the root of the issue, there are just as many people who have played a part. Issues with things such as the real estate market and government

Object-Oriented Technologies Essay Example | Topics and Well Written Essays - 500 words

Object-Oriented Technologies - Essay Example A vivid example of these technologies is human-machine interface simulator. The human-machine interface simulator has a kind of on-line object-oriented database model that describes the hierarchical structure of man-machine interface equipment. The dynamic changes of various sensors and actuators in the man-machine interface system can be simulated by rewriting the corresponding attributes of the instrumentation and controls equipment in the object-oriented database in accordance with the dynamic changes of both the plant simulator and the human model simulator. The on-line object-oriented database of the man-machine interface can be constructed easily by using a special graphic editor with icons. The object-oriented technologies are based on analysis of the data. In this case, †the information or object model contains the definition of objects in the system, which includes: the object name, the object attributes, and object relationships to other objects† (Object-Oriente d Analysis 2007). Some other devices move or deform to simulate the shapes of virtual objects. Users can physically contact the surface of the virtual object. The new interface devices are also based on object-oriented technologies. Deformation of the screen converts the two-dimensional image from the projector into a solid image. The main factors of object-oriented programming include â€Å"correctness, robustness, extendibility and reusability† (Meyer 557). In sum, a goal of object-oriented technologies is to guide technological design to optimize interactions between human operators and the systems they use

Wall street Journal write-ups Essay Example | Topics and Well Written Essays - 500 words

Wall street Journal write-ups - Essay Example Mention also of subprime lending as a possible instigator. Outlining further the history of economic crisis and how such circumstances play into crisis like these. How these crisis can have multiple causes and many intricacies. In the process of moving forward to find a solution to this financial crisis, many different options are available for consideration. The need to look at a situation like an economic crisis with logic and rational thinking, rather than emotions. Social Psychologist suggestion that when in doubt, people look to believe whatever they can to get them through. The article makes reference to the issue of regulatory practices which goes with the discussion in Chapter 12 having to do with regulation and its impact. Detailed in the section â€Å"Effect of Regulation on the Actions of Employers† Pages 573-575. The discussion which Claomiris sets forth to have is quite relevant for the times. The issue of how the many different circumstances that can occur could lead to such an economic downturn for many people. It is of the utmost importance to look at the larger picture that comes with the issue of economics and how best to aid an ailing economy. To formulate such solutions without the presence of emotional bias, but rather an educated approach with a rational mind. As is the case with many things, the history of what has happened in the economy before, both at home and abroad, is something that can be quite useful to analyze and consider as Claomiris suggests in his writing. Countless economic crisis have in fact occurred over the years. Each situation being individually different, but also having a central theme that can be tied in with others to find a central path towards a solution. As there are multiple circumstances at the root of the issue, there are just as many people who have played a part. Issues with things such as the real estate market and government

Strategic sales management Essay Example | Topics and Well Written Essays - 3750 words

Strategic sales management - Essay Example The process of having a good human resource base does not end with recruiting people as it is equally important to have motivated employees who can easily align their personal objectives with the organizational objectives so as to bring about organizational efficiency and generate competitive advantage. In order to have motivated employees, it is necessary to ensure a proper job fit so as to align the objectives of the employees and the employers. This requires a good recruitment strategy that would actually help in selecting a set of individuals who would be able to align themselves with the job responsibilities as well as the working culture in the organization. This would also boost up the morale of the employees who would be motivated to take up the job responsibilities (Griffin & Moorhead, 2009, p.118). The present study would be based on analysing the recruitment and staffing issues for the FMCG giant Procter & Gamble. The choice of the organization assumes significance as the company is considered to be among the largest FMCG companies of the world having its operations in diverse geographies with a wide product portfolio. The study would analyse the present recruitment policy of the organization and would try to find out the possible shortcomings in the strategies of recruitment and staffing presently adopted and implemented by the company. It would also try to formulate a proper recruitment and staffing strategy for the organization which would also include the framework for compensation, incentives and reward programs so as to motivate the employees to provide their best effort at the organization. About the Company Procter and Gamble (PROCTER & GAMBLE) is one of the most coveted FMCG Company of the world. The organization has its headquarters based in Cincinnati, USA and successfully operates out of 180 different diverse geographic nations with a wide array of product offering. The strengths of the organization can be analysed from the fact that its market capitalisation is greater than the GDP levels of many nations. The company also has a well defined policy of serving the society through a well knit policy of corporate social responsibility. The organization also has a well defined recruitment and staffing policy that helps it to churn out the best possible employees. It also has a raining and development program that trains employees to meet the standards required to bring about efficiency in organizations like PROCTER & GAMBLE (Procter & Gamble, 2011). Recruitment strategy Procter and Gamble follows a highly rigorous and comprehensive framework for recruitment and selection. The candidates selected for the organization are generally asked to go in through a rigorous session of numerous rounds of interviews. In the initial strategy, the candidates are asked to appear for an interview that tests the candidate’s ability to produce high volumes of quality work. The candidates pass through two rounds of filtering after w hich a test of general knowledge and general aptitude is conducted. The extent of success in these tests determine the level of efficiency of the candidate

Socratic Method Essay Example for Free

Socratic Method Essay Since the formulation of the Socratic Method, it has been made reasonably clear that the quest for knowledge is based on firstly knowing that one does not know everything and secondly that the only way to know more about anything is to ask more questions. This does not imply of course that one simply propound any knowledgeable person with a barrage of question. This simply suggests that perhaps not accepting everything at face value without any verification as to its truth or validity is simply not the way to learn. From the earliest years, the questions, what, who, how, when, where and the all time favorite, why, have been uttered at least a dozen times by any single person. While these are not the keys to critical thinking, they do form an important foundation of critical thinking and that is that it challenges the current knowledge and pushes people to find out more about things and not simple be content with what is present. Herein lays the first benefit of critical thinking. It challenges the mind to ask more questions and remains at the very center of the quest for knowledge. Without critical thinking, everything in itself would become the rule and nothing would ever be the exception. A falling apple would be a different rule in itself and not connected to a flying bird when in it is in fact clear that through the exercise of critical thinking gravity and all the other forces are at work on these two objects. Secondly, critical thinking pushes at boundaries. To simply say that a truth is truth in itself is naive. Critical thinking plays an important role in all of this because it does not alter the truth but simply brings more of it into light. It reveals and enlightens and only constricts those who are too bound and caught up in the piece of truth that they have come to know. Critical thinking provides other clear benefits but none as important as its role in uncovering the complete truth and driving the quest for knowledge for the benefit of all mankind. After all, critical thinking in itself would never even be the subject of this discussion if it never existed.

Advantages And Disadvantages Of Supercritical Fluid Chromatography Engineering Essay

Advantages And Disadvantages Of Supercritical Fluid Chromatography Engineering Essay Even though high performance liquid chromatography is a widely used technique for extractions of analytes in many classes, SFC has clear advantages over it. In HPLC a substantial amount of organic solvent is generated with each extraction, which then needs to be disposed. However, the disposal of the organic solvents is expensive at $5 $10 per gallon, whereas SFC uses considerably less or no organic solvent which leads to a decrease in analysis costs [1]. In replacement of organic solvents an inert environmentally friendly mobile phase is used, often carbon dioxide which can be collected from the atmosphere, as it is energy efficient in the isolation of the desired products [2]. Also without the use organic solvents the product is more concentrated compared to HPLC where the solvent must be evaporated, without the need to evaporate any solvent there is a reduction in energy and labour costs [2]. SFC is similar to gas chromatography (GC) in that it has a lower viscosity and higher diffusion coefficient than HPLC which allows for quicker, more efficient separations as it more effective at entering porous solid materials than liquid solvents. The separation time can be cut down from hours or days to a few tens of minutes [3]. As seen in Table 1, supercritical fluids lie between liquids and gases, which allows for SFC to use features of both HPLC and GC. Due to supercritical fluids having gas like and liquid like density it has a greater solvating power so SFC has a larger molecular range which includes non-volatile molecules which methods like GC do not include [1, 4]. Also, unlike GC which does not analyse thermally unstable compounds, SFC is able to due to the low critical temperatures of supercritical fluids such as carbon dioxide (31oC) [1] ; an advantage of supercritical fluid carbon dioxide is that it has a varied solvating strength that allows for selective extractions [5]. Along with this by altering the temperature and/or pressure it is possible to achieve higher selectivity. The range of detectors is also wider for SFC compared to GC or HPLC this is because in SFC the mobile phase can be liquid or gas like, so GC and HPLC detectors can be used [1]. For example SFC with flame ionization detection (FID) can provide quantification of resolved materials with a sensitivity of 0.1 ng [4]. Due to the range of detectors available for SFC and the low critical temperature of the carbon dioxide mobile phase, the detection and analysis of thermally labile compounds has been successful [3, 5]. Another advantage SFC has over HPLC is separation of chiral compounds, in HPLC the process is very time consuming, in SFC however, due to the lower viscosity of the supercritical fluids, the chiral separation can be run at a flow rate of up to 5 times faster than that of the HPLC all while avoiding pressure build up. The higher flow rate of SFC consequently means that the productivity is higher than HPLC methods [2]. When used in large scale extractions, fluid carbon dioxide can be recycled and then reused this minimize the amount of waste generated [3]. Property Gas Supercritical Fluid Liquid Density g/cm3 (0.6-2) x 10-3 0.2-0.5 0.6-1.6 Diffusion Coefficient cm2/s (1-4) x 10-1 10-3-10-4 (0.2-2) x 10-5 Viscosity g cm-1 s-1 (1-3) x 10-4 (1-3) x 10-4 (0.2-3) x 10-2Table 1: Comparison of Properties of Supercritical Fluids, Liquids and Gases [1] Due to the fact that SFC has features of both GC and HPLC, SFC has diversity in the columns that can be used which are either open tubular (GC) or packed (HPLC). In packed column SFC by choosing suitable column dimensions and particle size [6], this can cause an increase in the number of theoretical plates (over 100,000) [2, 6]. Further advantage is SFC is very clean; mobile phase contaminants are usually trace quantities of other gases. The mobile phase is very free of dissolved oxygen and is not particularly reactive and the mobile phase is easily and rapidly removed [2]. A disadvantage of using carbon dioxide as the mobile phase is it does not elute very polar or ionic compounds; this is overcome by using an organic modifier. However, there are some disadvantages of SFC these include that if molecules are highly polar they are not soluble in the mobile phase. Usually SFC only moves a small amount of a large specimen onto the column Limited availability However, these limitations have been overcome through instrumental modifications that more appropriately address purifications of micro-scale and nano-scale quantities of physiological molecules. More sophisticated 2D systems (2D-SFC) allow for the interfacing of 2 SFC columns having different column coatings or packing and thus provide for orthogonal separation capabilities [2]. Instrumentation used in SFC Originally, SFC instruments were based on HPLC designs with some modifications, however now the design includes a pumping system, modifier module, post-column nozzle and a separator detector [2]. The mobile phase in SFC is pumped as a liquid and then heated up past supercritical temperature until it reaches the supercritical region. The mobile phase passes through the injection valve before the sample is introduced, which carries the sample into the analytical column. To ensure the mobile phase stays supercritical, pressure restrictors are placed at the sides of the detector or at the end of the column. The pressure restrictors are heated as too avoid clogging [7]. As SFC uses a supercritical fluid as mobile phase, there are two possible types of column setup; one setup is HPLC like which consist of two reciprocating pumps these allow the mobile phase to mix and the introduction of a modifier, a packed column which are placed in an oven the detector used is an optical detector and the pressure and flow rates can be controlled separately [7]. Packed column SFC has recently become popular again over the past decade due to drug discovery and the pharmaceutical industry, as it offers the use of an environmentally friendly mobile phase, carbon dioxide, decrease in waste generation and provides purified materials even on a large scale, when used for drug discovery packed SFC is usually coupled with a mass spectrometer detector [2, 8]. In SFC there are lower eluent viscosity and higher diffusion coefficient which as a result lead to an increase in efficiency and a shorter separation time, the low viscosity causes only slight pressure drops which in tu rn allows for the flow rate to be quicker (3-5 mL min-1) compared to that of HPLC (typically ~1 mL min-1) [1, 8]. The other column setup is capillary SFC which is an extension of GC that includes a syringe pump and a capillary column inside a GC oven with a restrictor with a flame ionisation detector (FID), however, in capillary SFC the flow rate of the pump controls the pressure of the system [6, 7]. Other detection methods are also used for capillary SFC one method is Fourier transform infrared (FT-IR) spectrometry. Capillary SFC is used for high separation power and is more suited for fluids with low density. However, capillary columns have some limitations these include sample loading capacity, detection limits and quantitation [6, 7]. As mentioned FID is mostly used for capillary SFC, although in certain cases FID can be used with packed column SFC when a non-flammable mobile phase is used. However, the mobile phase that is used is usually carbon dioxide which requires an organic modifier to deactivate any unbounded silanol groups in the stationary phase [10] thus causing the mobile phase to become flammable this in turn causes a high background signal and a loss of sensitivity. Alternatively, modifiers like esters or lower alcohols can be used in packed column SFC in order to improve the elution of polar compounds [9]. However, to avoid the use of modifiers, open-tubular capillary columns can be used, since silanol groups are not present in the stationary phase [10]. Compared to capillary columns, packed columns display higher efficiency per unit time; also separations can be transported directly from analytical or preparative liquid chromatography (LC) to SFC. Moreover, a standard liquid chromatograph can easily be converted into a supercritical fluid chromatograph [11]. It has was found that certain separations that were developed on a 50 ÃŽÂ ¼m i.d. capillary column can be repeated with the same or better performance on a 1 mm i.d. (microbore) packed column. The packed column system has the additional advantage of yielding excellent peak area precision. It is also shown that the combination of water and formic acid is an effective modifier for CO2 which can be used with FID [6]. A study using the water and formic acid modifier was conducted by H. E. Schwartz et al. formic acid is used as it has low background noise and therefore is more favourable, however another problem arises when using this modifier and that large gradient humps appeared during the run, these were most probably because of organic impurities in formic acid. A way round this problem is that water is added to the carbon dioxide via the use of an aquafier system, the aquafier system used by H. E. Schwartz et al. was a 15 cm x 4.6 mm i.d. silica column (100-200 mesh) that was saturated with ca. 40% w/w water. The column was placed between the pump outlet and injection valve. A test mixture of the formic acid and water modifier was performed by H. E. Schwartz et al. and prodcued the chromatogram as seen in Figure 1[6]. Figure 1 Chromatogram of a test mixture of formic acid/water/CO2 mobile phase. Peak identification (from left to right): n-eicosane, anthraquinone, n-triacontane, tocopherol acetate, cholesterol [6]. In Figure 1 the baseline rises this was due to the pressure program used, however due to the addition of water to the mobile phase which prevented the accumulation of formic acid on the head of the column no hump is visible. In Figure 1 it can also be seen that all the peaks have good shape and resolution even for the more polar compounds like anthraquinone, tocopherol acetate and cholesterol [6]. Mobile phases and stationary phases used in SFC In SFC the density of the mobile phase is about 200-500 times greater to that in gas chromatography. Compounds with high molecular weights are not usually detectable in gas chromatography, however with the density of the mobile phase being greater they can therefore be chromatographed [12]. A wide range of compounds have been tested for use as SFC mobile phases, however, a variety of these required special conditions, and would therefore not be suitable. This resulted in carbon dioxide CO2 being used as it was easily obtainable, low cost and safe [13], along with the critical temperature being 31oC and critical pressure being 73.8 atm [14]. A problem with CO2 as a mobile phase in a packed column is that if CO2 mobilizes a species then there is a possibility that the compound will be irreversibly adsorbed onto the column, this is because of the high activity of most sorbents, this does not happen in capillary SFC as inert fused silica open-tubular column are used. To avoid adsorption onto the column, surface activity needs to be decreased; this has been achieved by using modifiers [14]. There are two main reasons why modifiers are added to the mobile phase, first is that only a small amount of modifier is added in order to deactivate the sorbent active sites, second is when the modifier is added in higher concentrations (level of modifier needed is à ¢Ã¢â‚¬ °Ã‚ ¥1%)it improves the solubility of the analyte in the mobile phase [14]. One problem with using modifiers is they have a high response when a FID is used; this high response causes an increase in the baseline. The alternative to using FID which helps relieve this problem is the use of a ultra-violet absorption detector, although it is not as applicable to organic compounds compared to FID [14]. This is only true for packed SFC, as when capillary SFC is used most separations are done using only CO2, which is compatible with FID. Having only CO2 as the solid phase can cause slight defects on the chromatograms such as very broad peaks and not well resolved, as well as longer retention times, this is solved by adding a small amount of water to the mobile phase, hence improving the peaks and decreasing the retention time [12]. Modifiers which can be used with the mobile phase include methanol, acetonitrile, chloroform and formic acid. Methanol is the most popular modifier being used in both packed and capillary SFC, even though the addition of water speeds up elution of polar compounds in capillary SFC [12]; methanol has a greater effect when used with silica-packed columns [14]. The solubility of methanol, acetonitrile and chloroform in CO2 was studied by K. L. Maguire and R. B. Denyszyn, they found out that when the pressure is below 90 for methanol/CO2 there was little effect on solubility, but when raised above 90 there was a substantial increase. Acetonitrile/CO2 had very little pressure dependence but small temperature dependence. Finally, chloroform/CO2 both pressure and temperature had a small effect on solubility, when either was raised the solubility of chloroform increased [14]. Research by G. L. Pariente and P. R. Griffiths showed when carboxylic acid groups were present in the analyte the retention time was greatly increased while still using CO2 mobile phase. The cause of this could be due to that the solubility of these polar molecules is low and the solvation is not great enough to overcome the strong hydrogen bonds. The alternative mobile phase used was chlorofluorocarbon (CCl2F2), in comparison to CO2 which had a capacity factor greater than 20 for isophthalic acid; CCl2F2 had a capacity factor of 3.9. These results suggest that CCl2F2 has sufficient free energy of solvation to overcome the hydrogen bonds [14]. Even though CO2 ­ is the most extensively used mobile phase it is no more polar than hexane [15], so alternatives including CCl2F2 have been investigated, however the critical temperatures must not be too high as one of the main advantages of SFC is that elution can take place at mild temperatures. Another example is ammonia (NH3), as it possesses a high dipole moment and relatively low critical temperature, however supercritical NH3 reacts with siloxane linkages and when left for an extended time the siloxane stationary phase for capillary SFC breaks down too [14]. Therefore, a more useful way of eluting polar compounds is CO2  ­and the use of a modifier [15]. For packed SFC more or less all of the stationary phases used in HPLC are used in SFC, most of these are silica-based, chemically bonded or encapsulated, or polymeric [8]. Evaluation of stationary phases of SFC was originally carried out by Schoenmakers et al. this was however, only done using pure CO2 as the mobile phase, and certain phases did not perform well, if a modifier was used these phases would have performed better. When CO2 and a modifier is used as a mobile phase the stationary phase also becomes modified in that both CO2 ­ and the modifier adsorb onto the stationary phase. Depending on the stationary phase depends on the level of adsorption, for CO2 all phases adsorb the same but more polar phases adsorb more modifier than less polar phases. This causes the stationary phase to become more polar than the mobile phase, which in turn will cause polar solutes to interact more with stationary phase increasing retention time. Other stationary phases that have been studied include octadecylsiloxane-bonded silica (ODS), cyanopropylsiloxane- bonded silica, divinylbenzene-ODS, polydimethylsiloxane and porous graphitic carbon (PGC) stationary phases in supercritical [8]. In capillary SFC a problem arises in that normal GC stationary phases dissolve in the supercritical fluid mobile phase as they have a high solvating power. In order to correct the problem a non-extractable stationary phase is needed, examples of this are bonded phase where the stationary phase is attached to the column to surface groups via covalent bonds and cross linked phase where polymer chains within the stationary phase are attached to each other. In order to create non-extractable stationary phase, the process of coating must be undertaken, there are two types of coating, dynamic and static. The most favoured for SFC is static, as dynamic can lead to poor column efficiency and a thick stationary phase is not possible. In static coating the stationary phase is first dissolved in supercritical fluid and forced into the column, to avoid the removal of the phase cross link phase is used as it occurs between the polymers and not between polymer and substrate, and therefore can be applied to glass and fused silica columns [16]. Conclusion